"PDB format not supported" using .NET portable debugging information

For the last couple of days I have been looking for a problem - with the conclusion:

My Visual Studio 2017 debugger cannot work with PDB in portable format in .NET Framework projects.

In the portable format, I mean going to the project settings, then to Build -> Advanced, and then selecting portableunder Debugging information.

When I start debugging a .NET Framework project built in this way, breakpoints do not fall.

The breakpoint will not currently be hit.  No symbols have been loaded for this document.

When I pause the debugger and look for the reason why it did not load characters, it says (under Symbol load information):

PDB format not supported

.NET Framework. , , . .NET 4.5.2 4.6.2.

, .NET Core.

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