The question is very, very broad. Interpreting it as "can I use Javascript on the server":
In principle, of course, Javascript is a very powerful language, so you can create a server version on it, as well as on the client side (and if you use client-side scripts, you get certain reuse advantages using Javascript on the server).
- Apache v8cgi ( FastCGI Javascript , Google freaky-fast V8).
- Microsoft IIS Javascript (JScript) ( ), ActiveX (, , ..).
- JVM, Rhino, Javascript Java ( ) , Java — , .
- v8cgi, , Google V8.
- , , chromeserver ( , , m ).
- ServerJS NodeJS.
- CommonJS.
Etc. .. .. .
, , PHP. - Rhino Java JScript IIS (- , ), , , Javascript . , wiki (), , , PHP, Javascript .