In your configuration file, you can specify your own toolbar (and leave the save button).
For example, my configuration:
CKEDITOR.editorConfig = function( config )
{
config.uiColor = '#F6F6F6';
config.fontSize_sizes = '8/8px;9/9px;10/10px;11/11px;12/12px;14/14px;15/15px;16/16px;18/18px;20/20px;22/22px;24/24px;26/26px;28/28px;36/36px;48/48px;72/72px' ;
config.forcePasteAsPlainText = true;
config.format_tags = 'p;h2;h3;h4;h5;h6;pre;div'
config.height = "400px";
config.skin = 'kama';
config.undoStackSize = 90;
config.width = "98%";
config.disableNativeSpellChecker = false;
config.scayt_autoStartup = false;
config.toolbarCanCollapse = false;
config.toolbar = 'Cms';
config.toolbar_Cms =
[
['Source'],
['Cut','Copy','Paste','PasteText','PasteFromWord'],
['Undo','Redo','-','SelectAll','RemoveFormat'],
'/',
['Bold','Italic','-','Subscript','Superscript'],
['NumberedList','BulletedList','-','Outdent','Indent','Blockquote'],
['JustifyLeft','JustifyCenter','JustifyRight','JustifyBlock'],
['Link','Unlink','Anchor'],
['Image','Table','SpecialChar'],
'/',
['Styles','Format','FontSize'],
['TextColor'],
['Maximize', 'ShowBlocks']
];
};