Good question.
The following is a description of t16web.lanl.gov/Kawano/gnuplot/plot4-e.html#5.12.
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#!/bin/bash
echo "2010-11-17 13:30:01,1
2010-11-17 13:30:12,3.1
2010-11-18 13:30:23,2.1
2010-11-19 13:30:34,4" > two_axis.dat
gnuplot<<EOF
set term png small
set output "two_axis.png"
set size 1.0,0.8
set bmargin 0
set lmargin 3
set yrange [0:5]
set multiplot
set origin 0,0.2
set datafile separator ","
set xdata time
set timefmt "%Y-%m-%d %H:%M:%S"
set format x "%H:%M"
set xrange["2010-11-17 12:00:00":"2010-11-19 14:00:00"]
plot "./two_axis.dat" using 1:2 with lines
set origin 0,0.1
set noytics
unset mxtics
unset border
set xtics nomirror scale 0 format "%Y-%m-%d"
set xtics "2010-11-01 00:00:00", 86400, "2010-12-01 00:00:00"
plot "./two_axis.dat" using 1:(\$2-1000) with lines notitle
unset multiplot
set output
set term pop
EOF

,
Tom