Of course, you can develop for Stackless, but there is currently no specialized Stackless support. This means that you will find experience editing code, and the REPL window is working fine. But profiling and debugging that rely on sys.settrace will not work for tasklets.
If you install Stackless via MSI, PTVS will pick up the installation just like any regular CPython installation. If you installed it through some other mechanism, you need to go to Tools-> Options-> Python Tools-> Interpreter Options and configure your own interpreter using the Add Interpreter button.
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