You can specify a Transparent KeyColor for a certain color value of the inverse form colors for the clickthru area, this color should be different from the mesh color you selected.
VB.Net, , #
Private Sub frmTest_Paint(ByVal sender As Object, ByVal e As System.Windows.Forms.PaintEventArgs) Handles Me.Paint
Dim rc As Rectangle = New Rectangle(0, 0, Me.Width - 1, Me.Height - 1)
Using br As New Drawing2D.HatchBrush(Drawing2D.HatchStyle.Cross, Color.Silver, Color.Transparent)
e.Graphics.FillRectangle(br, rc)
End Using
End Sub
Private Sub frmTest_Load(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles MyBase.Load
Me.TopMost = True : Me.Opacity = 10% : Me.WindowState = FormWindowState.Maximized
Me.BackColor = Color.White
Me.TransparencyKey = Color.White
Me.FormBorderStyle = Windows.Forms.FormBorderStyle.None
End Sub