You can use BeautifulSoup to parse the answer to get selection options
import mechanize
from BeautifulSoup import BeautifulSoup
br = mechanize.Browser()
resp = br.open('your_url')
soup = BeautifulSoup(resp.get_data())
second_select = soup.findAll('select', name="mv_searchspec")[1]
You cannot do something like this br['mv_searchspec'] = 'foo', because obviously this is ambiguous. You have to do it though
br.select_form(nr=0)
controls = br.form.controls
controls[desired_index]._value = 'your_value'
...
br.submit()