In the latest version of Angular RC4, Rxjs is available with node_modules or npmcdn.com .
Successful plunker but not using .umd.js
http://plnkr.co/edit/B33LOW?f=systemjs.config.js&p=preview
This is a screenshot of the Network tab for downloading individual files. 
Of course, this setting allows you to load many individual RxJS files because they read the files individually, not .umd.js
However, like other AngularJS files, when I try to use a single umd.js file, the following error occurs.
GET https://npmcdn.com/ rxjs@5.0.0-beta.6 /bundles/Subject 404 () GET https://npmcdn.com/ rxjs@5.0.0-beta.6 /bundles/Observable 404 () GET https://npmcdn.com/ rxjs@5.0.0-beta.6 /bundles/observable/PromiseObservable 404 () ...

Unsuccessful plunker tries to use .umd.js and system.config.js
http://plnkr.co/edit/rVUNyz?p=preview&f=systemjs.config.js
systemjs.config.js
var map = { 'app': 'app', '@angular': 'https://npmcdn.com/@angular', // sufficient if we didn't pin the version '@angular/router': 'https://npmcdn.com/@angular/router' + routerVer, '@angular/forms': 'https://npmcdn.com/@angular/forms' + formsVer, '@angular/router-deprecated': 'https://npmcdn.com/@angular/router-deprecated' + routerDeprecatedVer, 'angular2-in-memory-web-api': 'https://npmcdn.com/angular2-in-memory-web-api', // get latest 'rxjs': 'https://npmcdn.com/ rxjs@5.0.0-beta.6 /bundles', 'ts': 'https://npmcdn.com/ plugin-typescript@4.0.10 /lib/plugin.js', 'typescript': 'https://npmcdn.com/ typescript@1.9.0-dev.20160409 /lib/typescript.js', }; //packages tells the System loader how to load when no filename and/or no extension var packages = { 'app': { main: 'main.ts', defaultExtension: 'ts' }, 'rxjs': { main: 'Rx.umd.js', defaultExtension: 'js' }, 'angular2-in-memory-web-api': { main: 'index.js', defaultExtension: 'js' }, };
It seems that rxjs does not use the package section at all. I do not see the difference between using the rxjs section in packages.
Just for this plunker to work, I need to change the map section to the next without bundles
'rxjs': 'https://npmcdn.com/ rxjs@5.0.0-beta.6 ',
My question is: "Is there a way to use Rx.umd.js with an Angular2 application?