1. Do you need your projects to be built in Debug or Release to profile them?
Usually you use Release mode.
6. Can you recommend any good guides on using the VS2008 profiler?
Step 1, download ANTI Profiler .
Step 2, follow the simple instructions on the screen.
Step 3, see easy-to-read reports.
Seriously, Microsoft's profiler is rubbish compared to ANTS.
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