When I installed VS2008 and he asked me to choose my layout, I accidentally chose web development. Is it possible to go back and apply it to a C # layout?
Yes:
Go to Tools / Import and Export Settings / Reset All Settings.
Tools-> Import and Export Settings ... In the dialog that appears, select Reset All Settings, then follow the instructions (save or not save the current settings as you see fit) to select the Default Settings Set and select C #