There is a good selection of modules: http://www.iis.net/downloads (mainly IIS7 modules)
My favorite is probably the streaming module, which limits bandwidth after an intuitive burst of data, optimizing the transmission of progressive downloads: http://www.iis.net/media .
As for IIS6, SAFileup was useful for allowing large file transfers by splitting files onto a disk rather than loading data into memory (ISAPI + .net Module plugin). However, this is a commercial product, and I think they can be free or cheaper alternatives these days.
There are also several dynamic image resizing modules that are extremely useful.
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