What is post-oriented middleware with the Python API? Which of them did you use and recommend (or not)?
I remember that some people allegedly used distribution for message queues at http://www.spread.org/ , but I have no personal experience with it.
For ActiveMQ there is
OpenWire-based Python client at http://hiramchirino.com/old-blog/2009/07/openwire-python-client-for-activemq.html
many Python clients based on the Stomp protocol at http://stomp.codehaus.org/Python
I would also look at ZeroMQ .