This is similar to a stream already created: Mixed mode assembly in .NET 4
Using the application configuration, I managed to get the assemblies to work on .NET 4. On the XP machine, I installed only .NET 4 (without .NET 3.5 or 2.0) and tried to run the embedded application. It cannot load the mixed-mode assembly built in the 3.5 framework in .NET 4, without the .NET 3.5 framework on the machine.
Why should this depend on .NET 3.5 when I force the application to run on .NET 4 using the App config?
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