If you need something reasonably complex or flexible, it is better to use Dynamic and DynamicModule instead of Manipulate . The only exception is if you write demonstration .
For example, a very simple way to do what you want (in fact, you donβt even need Row and Slider if you just want to change changeme manually.)
changeme=8; p[x_]:=Plot[Sin[t],{t,1,x}]; Row[{"x \[Element] (1, ",Dynamic[changeme],") ",Slider[Dynamic[changeme],{2,9}]}] Dynamic[p[changeme]]
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