In general, this warning means that in some places the tab is used for indentation and spaces in another.
for instance
"\t<p>Text goes here\n </p>"
Here, the first line is indented with a tab, and the second with four spaces. The choice depends on your preference. Personally, I prefer spaces (Untabify in this case). However, one tab takes up one byte, and indentation with spaces takes four. If your html is about 1000 lines long, using tabs will reduce your final HTML to 3000+ bytes.
Tabs and spaces are recognized by all systems and usually take up four spaces, so they should look the same in all regular editors. There is no difference in rendering, but loading times may vary for the above reason.
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