Drupal does not save any changes to administrator settings

I have a strange problem in drupal. When I try to change the _any_ parameter in the drupal admin (performance caching, temp-directory in the file system, default filter under filters, etc.), I get a message that the changes were saved successfully, but the values โ€‹โ€‹donโ€™t to change.

I donโ€™t know where to start debugging, since this is such a common problem. I checked the rights of all files / folders and the database connection. Seems beautiful.

Has anyone experienced such a problem before?

edit: There is no error entry in the drupal log file.

edit 2: I just turned off each Contrib module. However, I cannot make any changes (for example) to the cache mode.

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Clear the cache in the application and check again. You can find it from

 Drupal 7: Administration > Configuration > Development > Performance (admin/config/development/performance) Drupal 6: Administer > Site configuration > Performance (admin/settings/performance) Click "Clear cached data" button below 
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