Image calibration

I have a series of mostly identical images taken over a period of time. However, objects in images change over time, and I would like to fix it. What good was that?

[EDIT] Well, I might have to explain why I'm going to do this. I took several series of x-ray images of objects at different x-ray energies. Now I want to compare an object with different energies, but since it is drifting, I must first correct the drift. The object does not have sharp edges or anything that otherwise would be easy to use for alignment. Therefore, I am looking for a more general method

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In general terms, this problem is known as image registration and is a large research topic in the image processing community. There are many different methods and algorithms, often specialized for image modality. Depending on your images, this can be easy, or it can be difficult. I would recommend using one of the registration methods found in file sharing.

Based on your description of your images, it seems that > this method should work well.

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