Yes, just make sure you target the .Net 2.0 framework.
You can see: Version Compatibility in the .NET Framework
The .NET Framework 4.5 supports backward compatibility with applications that were built with the .NET Framework versions 1.1, 2.0, 3.0, 3.5, and 4. In other words, applications and components built using previous versions of the .NET Framework will work with the .NET Framework 4.5. .
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