If I understand correctly, do you have images with a spatial length of (a)9 x 6 x 1.2 cm ^ 3 and (b)1.6 x 0.7 x 0.6 cm ^ 3? They are quite small and very different. I can imagine that if image 2 covers a very specific subarea of image 1 (because it is much smaller), you may need a good starting score to get the right result.
if input_imageit measures (b)and good_size_imagemeasures (a), and then with a call
flirt -in input_image
-ref good_size_image
-out output_image
-applyxfm
( initoption in this case is not absolutely necessary),
, . , ( ), . (a) (b) , . .
applyisoxfm, .
flirt -in small_image -ref small_image -out small_1mm -applyisoxfm 1
, (b) 1x1x1 ^ 3. , , , . , 0,5 , ?
FSL
, .