I think technically yes, but certainly not easy. You can configure the build process manually to use (freely available) compilers from the .NET 4. You will need to install .NET 4 manually and then roll your own build scripts from scratch if you want to fully integrate or manually compile your projects from command line
However, it is worth remembering that VS2005 did not have IntelliSense support or compiler integration for .NET 4, so you will not have anything pleasant in the IDE. Notepad could be easier!
Honestly, I'm not sure if this is what I consider an attempt!
Dan puzey
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