Your question is a bit unclear because you did not say which computers the web application runs on, which computer the USB device is on, and which computer yours.
Depending on the details, one possible solution would be to write an application for Chrome Packaged and use the API for Chrome USB . The application will need to be installed on a computer with a USB device, and then it can provide a user interface to the user or simply connect to a remote server and allow remote control of the device.
David grayson
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