The answer depends on asking additional questions, for example, how much you want to spend, what OS you use and what experience you have.
The database that I know of can handle such a massive scale: DB2, Oracle, Teradata, and SQL Server. MySQL may also be an option, although I'm not sure about its performance capabilities.
There are others, I'm sure, designed for mass-scale data processing that you offer, and you may also need to study them.
So, if your OS is not Windows, you can exclude SQL Server.
If you're going for less, MySQL might be an option.
DB2 and Oracle are mature database systems. If your system is a mainframe (IBM 370), I would recommend DB2, but there might be an option for Unix-based.
I don’t know much about Teradata, but I know that it is specially designed for a huge amount of data, so it may be closer to what you are looking for.
A more complete list of options can be found here: http://en.wikipedia.org/wiki/List_of_relational_database_management_systems
A decent database comparison is here: http://en.wikipedia.org/wiki/Comparison_of_relational_database_management_systems
100,000+ inserts the second one - this is a huge amount, no matter what you choose, you are looking to spend a fortune on equipment to handle it.