This worked for really weird heisenbugs. (I would also recommend getting a copy of Dave Argans's Debugging, these ideas are partly derived from his ideas!)
(0) Check the system RAM using something like Memtest86!
The whole system detects a problem, so create a test fixture that does all this. Say that this is a server thing with a graphical interface, you start it all with the help of a graphical GUI that makes the necessary input to provoke a problem.
This will not fail for 100% of the time, so you will have to endure it more often.
Start by cutting the system in half (binary chop). In the worst case scenario, you need to remove the subsystems one at a time. drown them out if they cannot be commented on.
Look, it still fails. Does this happen more often?
Keep the correct test records and change only one variable at a time!
In the worst case scenario, you use jig and you test for several weeks to get meaningful statistics. It's difficult; but remember that jig does the job.
I have no threads and only one process and I am not talking to equipment
If the system does not have threads, there are no communication processes and contacts; there is no hardware; it is difficult; heisenbugs are usually synchronized, but in the case without threads there are no processes, most likely it is uninitialized data or data used after release, either on the heap or on the stack. Try using checker like valgrind.
For problems with multi-threaded / multi-processor processes:
Try running it on a different number of processors. If it works on 1, try 4! Try setting the 4-computer system to 1. This basically ensures that everything happens in turn.
If there are threads or messaging processes, this can get rid of errors.
If this does not help, but you suspect that it is synchronization or threads, try resizing the OS timeout. Do it as good as your OS provider allows! Sometimes this led to the fact that racing conditions happened almost every time!
Finally, try to slow down on timelists.
Then you install a test joystick that works with debugger (s) attached everywhere and wait for the test clip to stop by mistake.
If all else fails, put the equipment in the freezer and run it there. The timing of everything will be shifted.