We can use the SMT solver to test our hypothesis that your formula can be simplified. You can go to http://rise4fun.com :
x = BitVec('x', 8) y = BitVec('y', 8) z = BitVec('z', 8) print simplify((x + z) ^ (y + z))
and the result, unsurprisingly, is:
x + z ^ y + z
This means that your formula cannot be simplified.
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