PyCharm 4.5.4 has a command called Save Document. It saves only the current file.
Go to Settings> Keyboard
Find "Save All" in the search box on the right. Find the Save All command, right-click on it, delete Cmd-S and add Cmd-Shift-S. He may warn you that this will remove Cmd-Shift-S from another command; Click "Delete."
Find "Save Document." Right-click on it and add the shortcut Cmd-S.
On Windows, use Ctrl-S instead of Cmd-S.
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